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Discontinuing GLP-1 Treatment Associated With Up to 60% Weight Regain, With Brajan Budini
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Researchers and the public alike have questioned what happens when someone stops taking GLP-1 drugs. A recent study suggests that most patients maintain weight loss. Read about the research via the link
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ISPOR 2025: Exploring reasons for GLP-1 discontinuation
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Time to Discontinuation of GLP-1 RAs, Kaplan–Meier Plot, n=4791
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What happens when people stop GLP-1 weight-loss drugs? A recent paper in eClinicalMedicine analysed weight regain after stopping GLP-1 receptor agonists using a systematic review and nonlinear meta-regression of 48 studies. Because
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New real-world data show that over half of people who stop GLP-1 weight-loss drugs regain some weight within a year. The findings align with clinical trial data: once treatment stops, weight typically
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Proportion of Patients Who Discontinued GLP-1 RA Therapy, n=4791
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